STUDIES OF PYRIMIDINE NUCLEOTIDES WITH OROTIC ACID-2-C14 AND P32
نویسندگان
چکیده
منابع مشابه
The incorporation of formate-C14, glycine-2-C14, adenine-4, 6-C14, and phosphate-P32 into nucleic acids.
nine labeled either with C'4 or N'5. Considerable controversy has developed as to which one of these tracer compounds gives an accurate measurement of the “relativeturnover-rate― of the nucleic acids. In order to determine the “absolute turnover rate― of the nucleic acids, it is necessary to know the specific activity of the immediate precursor of the nucleic acids. Since even the ident...
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Thioacetamide, adminlstered in a dose of 50/mg/kg for 9 days, produced a profound effect on the distribution and labeling of ribonucleic acid (RNA) of the rat liver. The amount of p-RNA (released by phenol into the aqueous phase) and r-RNA (which re mained in the phenol), was increased twoto threefold in the nuclei. In the nucleoli, the amount of p-RNA was doubled, and the r-RNA was increased b...
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* The data in this paper have been taken from a thesis presented by Ray Wu to the Graduate School of Arts and Sciences of the University of Pennsylvania in partial fulfilment of the requirements for the degree of Doctor of Philosophy. An abstract of a preliminary report of this work has appeared (1). Aided by a grant from the American Cancer Society, administered by the Committee on Growth of t...
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The incorporation in vivo of compounds labeled with N15 or Cl4 into the purines and pyrimidines of nucleic acid has been repeatedly demonstrated (e.g. (l-3)). W e wish to report observations on the incorporation of radioactive erotic acid in vitro into the pyrimidines of the nucleic acid of rat liver slices. It is believed that this procedure will readily permit the study of precursors of nucle...
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The metabolism of pyruvic acid in the light and dark by Scenedesmus has been examined with two aims: to study the relationship of its metabolism to that of the intermediates of C1402 fixation and to compare its metabolic fate with that of hydroxypyruvate. The metabolism of hydroxypyruvic acid was compared with that of C1402 fixation in order to ascertain whether it might be a photosynthetic int...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1953
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)66186-1